LRATD2

Across TCGA patient cohorts, LRATD2 mutation is significantly associated with the RNA expression of many other genes, with 1,403 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible LRATD2-associated genes across cancer lineages are MIR6515, RNU6-43P, and RNU6-1228P. Each is linked with LRATD2 in more than 1 cancer types. Because this analysis shows association rather than direction, both LRATD2-to-partner and partner-to-LRATD2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR6515 grouped by LRATD2-low versus LRATD2-high in BRCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LRATD2→partner) and Y-score (partner→LRATD2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	MIR6515 →	+0.717	+8.055	<.001	.007	3	2
UCEC	RNU6-43P →	+0.426	+2.402	<.001	.001	3	2
BLCA	RNU6-1228P →	+0.171	+4.444	<.001	.006	3	2
UCEC	RNA5SP164 →	+0.114	+4.253	<.001	.004	3	2
BLCA	RN7SKP272 →	+0.404	+4.304	<.001	.001	3	2
UCEC	PSMB7P1 →	+0.072	+2.899	<.001	.003	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,403 associations by consensus.

MIR6515 by LRATD2 expression — BRCA

Explore this box plot interactively →