LRATD1

Across TCGA patient cohorts, LRATD1 protein abundance is significantly associated with the protein abundance of many other proteins, with 9,857 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible LRATD1-associated proteins across cancer lineages are PLEKHO2, GMIP_S437, and KRT5_T24. Each is linked with LRATD1 in more than 3 cancer types. Because this analysis shows association rather than direction, both LRATD1-to-partner and partner-to-LRATD1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, LRATD1 versus PLEKHO2 in LSCC, with a Pearson correlation of -0.41.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (LRATD1→partner) and Y-score (partner→LRATD1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	PLEKHO2 →	-0.280	-0.684	<.001	<.001	3	4
LSCC	GMIP_S437 →	-0.603	-0.716	<.001	<.001	3	3
LSCC	KRT5_T24 →	+1.776	+0.925	<.001	<.001	3	3
LSCC	CDH1 →	+0.519	+0.783	<.001	<.001	3	3
LSCC	CYFIP2 →	-0.456	-0.885	.001	<.001	3	3
HNSC	DSP →	+0.684	+0.562	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,857 associations by consensus.

LRATD1 vs PLEKHO2 — LSCC

Explore this scatter interactively →