LRATD1

Across TCGA patient cohorts, LRATD1 mutation is significantly associated with the RNA expression of many other genes, with 1,107 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible LRATD1-associated genes across cancer lineages are DNAJB5P1, ST6GALNAC2P1, and MIR7159. Each is linked with LRATD1 in more than 2 cancer types. Because this analysis shows association rather than direction, both LRATD1-to-partner and partner-to-LRATD1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DNAJB5P1 grouped by LRATD1-low versus LRATD1-high in LIHC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LRATD1→partner) and Y-score (partner→LRATD1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIHC	DNAJB5P1 →	+0.214	+5.447	<.001	.005	3	3
BLCA	ST6GALNAC2P1 →	+0.068	+5.444	<.001	.002	3	3
BRCA	MIR7159 →	+0.630	+5.317	<.001	.006	3	2
LIHC	STSP1 →	+0.061	+6.305	<.001	.001	3	2
LIHC	HAUS6P2 →	+0.035	+5.447	<.001	.005	3	2
BLCA	RN7SL79P →	+0.279	+4.719	<.001	.003	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,107 associations by consensus.

DNAJB5P1 by LRATD1 expression — LIHC

Explore this box plot interactively →