LRATD1

Across TCGA cell cohorts, LRATD1 mutation is significantly associated with the RNA expression of many other genes, with 13 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible LRATD1-associated genes across cancer lineages are ARMC3, RSPO1, and OR2J1. Each is linked with LRATD1 in more than 1 cancer types. Because this analysis shows association rather than direction, both LRATD1-to-partner and partner-to-LRATD1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ARMC3 grouped by LRATD1-low versus LRATD1-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LRATD1→partner) and Y-score (partner→LRATD1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	ARMC3 →	+0.487	+3.392	<.001	.006	3	1
LARGE_INTESTINE	RSPO1 →	+0.019	+3.217	.001	.006	3	1
LARGE_INTESTINE	OR2J1 →	+0.002	+3.700	<.001	.009	3	1
LARGE_INTESTINE	ZNF469 →	+0.431	+3.333	.004	.009	3	1
LARGE_INTESTINE	OR51B2 →	+0.380	+2.876	.006	.009	3	1
BLOOD_Lymphoma	BANF2 →	+0.035	+4.643	.003	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 13 associations by consensus.

ARMC3 by LRATD1 expression — LARGE_INTESTINE

Explore this box plot interactively →