LPP

Across TCGA patient cohorts, LPP protein abundance is significantly associated with the RNA expression of many other genes, with 16,612 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible LPP-associated genes across cancer lineages are MYL9, CNN1, and LMOD1. Each is linked with LPP in more than 9 cancer types. Because this analysis shows association rather than direction, both LPP-to-partner and partner-to-LPP results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, LPP versus MYL9 in UCEC, with a Pearson correlation of 0.63.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LPP→partner) and Y-score (partner→LPP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	MYL9 →	+1.407	+0.675	<.001	<.001	3	10
UCEC	CNN1 →	+2.920	+0.852	<.001	<.001	3	10
UCEC	LMOD1 →	+2.051	+0.793	<.001	<.001	3	10
BRCA	FILIP1L →	+1.203	+0.426	<.001	<.001	3	10
BRCA	MSRB3 →	+1.476	+0.506	<.001	<.001	3	10
UCEC	PRKG1 →	+1.141	+0.818	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,612 associations by consensus.

LPP vs MYL9 — UCEC

Explore this scatter interactively →