LPIN2

Across TCGA cell cohorts, LPIN2 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,655 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible LPIN2-associated GO terms across cancer lineages are Cellular response to insulin stimulus, Regulation of cellular response to transforming growth factor beta stimulus, and Endocytic recycling. Each is linked with LPIN2 in more than 12 cancer types. Because this analysis shows association rather than direction, both LPIN2-to-partner and partner-to-LPIN2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Cellular response to insulin stimulus grouped by LPIN2-low versus LPIN2-high in URINARY_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (LPIN2→partner) and Y-score (partner→LPIN2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	Cellular response to insulin stimulus →	+0.045	+1.482	<.001	<.001	3	13
OVARY	Regulation of cellular response to transforming growth factor beta stimulus →	+0.044	+0.915	<.001	<.001	3	13
URINARY_TRACT	Endocytic recycling →	+0.054	+1.251	.002	.003	3	12
PANCREAS	Regulation of androgen receptor signaling pathway →	+0.098	+1.588	<.001	<.001	3	11
OVARY	Regulation of transforming growth factor beta receptor signaling pathway →	+0.045	+0.893	<.001	.001	3	11
SOFT_TISSUE	Macroautophagy →	+0.051	+1.067	<.001	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,655 associations by consensus.

Cellular response to insulin stimulus by LPIN2 expression — URINARY_TRACT

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