LPIN1

Across TCGA patient cohorts, LPIN1 protein abundance is significantly associated with the RNA expression of many other genes, with 11,508 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible LPIN1-associated genes across cancer lineages are LMO4, GPR157, and VAPA. Each is linked with LPIN1 in more than 4 cancer types. Because this analysis shows association rather than direction, both LPIN1-to-partner and partner-to-LPIN1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, LPIN1 versus LMO4 in BRCA, with a Pearson correlation of 0.38.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LPIN1→partner) and Y-score (partner→LPIN1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	LMO4 →	+1.288	+0.544	<.001	<.001	3	4
COAD	GPR157 →	-0.653	-0.278	.001	.008	3	4
LUAD	VAPA →	-0.518	-0.320	<.001	<.001	3	4
OV	ENOSF1 →	-0.638	-0.375	.008	.003	2	5
HNSC	TUBA1C →	-0.647	-0.267	<.001	.007	2	5
LSCC	MRPL43 →	-0.340	-0.226	<.001	.008	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,508 associations by consensus.

LPIN1 vs LMO4 — BRCA

Explore this scatter interactively →