LPCAT2

Across TCGA cell cohorts, LPCAT2 mutation is significantly associated with the RNA expression of many other genes, with 11 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible LPCAT2-associated genes across cancer lineages are REG1A, CRISP1, and OR10P1. Each is linked with LPCAT2 in more than 1 cancer types. Because this analysis shows association rather than direction, both LPCAT2-to-partner and partner-to-LPCAT2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, REG1A grouped by LPCAT2-low versus LPCAT2-high in BLOOD_Lymphoma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LPCAT2→partner) and Y-score (partner→LPCAT2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	REG1A →	+0.561	+3.700	<.001	.005	3	1
BLOOD_Lymphoma	CRISP1 →	+0.021	+4.247	<.001	.004	3	1
BLOOD_Lymphoma	OR10P1 →	+0.329	+4.209	<.001	.001	3	1
BLOOD_Lymphoma	OR2AK2 →	+0.048	+3.606	<.001	.002	3	1
BLOOD_Lymphoma	PRAMEF9 →	+0.028	+3.342	<.001	.008	3	1
LARGE_INTESTINE	ASPN →	+0.035	+3.426	.007	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 11 associations by consensus.

REG1A by LPCAT2 expression — BLOOD_Lymphoma

Explore this box plot interactively →