LPAR4

Across TCGA patient cohorts, LPAR4 mutation is significantly associated with the RNA expression of many other genes, with 2,124 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible LPAR4-associated genes across cancer lineages are LINC01202, SAMM50P1, and RNU6-178P. Each is linked with LPAR4 in more than 2 cancer types. Because this analysis shows association rather than direction, both LPAR4-to-partner and partner-to-LPAR4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LINC01202 grouped by LPAR4-low versus LPAR4-high in HNSC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LPAR4→partner) and Y-score (partner→LPAR4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	LINC01202 →	+0.689	+3.074	<.001	.008	3	2
UCEC	SAMM50P1 →	+0.081	+1.407	.004	.009	3	2
READ	RNU6-178P →	+0.557	+4.361	.001	.006	3	2
UCEC	LINC01607 →	-0.539	-3.066	<.001	<.001	3	2
ESCA	IGHD5-24 →	+0.957	+3.967	.001	.004	3	2
UCEC	RCC1 →	+0.444	+3.711	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,124 associations by consensus.

LINC01202 by LPAR4 expression — HNSC

Explore this box plot interactively →