LOXL4

Across TCGA patient cohorts, LOXL4 RNA expression is significantly associated with the protein abundance of many other proteins, with 11,136 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible LOXL4-associated proteins across cancer lineages are LMNA, TES, and STAB1. Each is linked with LOXL4 in more than 5 cancer types. Because this analysis shows association rather than direction, both LOXL4-to-partner and partner-to-LOXL4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, LOXL4 versus LMNA in UCEC, with a Pearson correlation of 0.28.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (LOXL4→partner) and Y-score (partner→LOXL4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	LMNA →	+0.718	+0.770	<.001	<.001	3	6
BRCA	TES →	+0.436	+1.222	<.001	<.001	3	5
OV	STAB1 →	+0.390	+1.129	<.001	.001	3	4
GBM	FBLIM1 →	+0.513	+0.467	.004	.005	3	4
GBM	FHL2 →	+0.777	+0.521	<.001	<.001	3	4
COAD	KCTD12 →	+0.551	+0.594	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,136 associations by consensus.

LOXL4 vs LMNA — UCEC

Explore this scatter interactively →