LNX2

Across TCGA patient cohorts, LNX2 mutation is significantly associated with the RNA expression of many other genes, with 2,384 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible LNX2-associated genes across cancer lineages are RN7SL504P, RPL34P3, and RNU6-347P. Each is linked with LNX2 in more than 2 cancer types. Because this analysis shows association rather than direction, both LNX2-to-partner and partner-to-LNX2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SL504P grouped by LNX2-low versus LNX2-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LNX2→partner) and Y-score (partner→LNX2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	RN7SL504P →	+0.034	+3.900	<.001	.008	3	3
HNSC	RPL34P3 →	+0.280	+5.505	<.001	.004	3	2
SKCM	RNU6-347P →	+0.092	+4.643	<.001	.002	3	2
UCEC	PIP4P1 →	+0.359	+1.847	.004	.009	3	2
UCEC	MRPL22 →	+0.329	+3.766	.001	<.001	3	2
UCEC	C15orf61 →	+0.470	+3.087	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,384 associations by consensus.

RN7SL504P by LNX2 expression — SKCM

Explore this box plot interactively →