LNX1

Across TCGA pan-cancer cohorts, LNX1 mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated LNX1 data layer compared with 24 for mass-spec protein and 8 for mutation status.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher LNX1 mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated LNX1 expression acts as an unfavorable survival marker, although some lineages such as UCEC and PDAC show a favorable association.

UCEC, PDAC, and CCRCC are the cancer types where LNX1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCEC	DFS	Quartile	All	0.959	0.675	.005	26	view →
PDAC	DFS	Quartile	III,IV	0.707	0.250	.016	19	view →
CCRCC	OS	Median	All	0.910	0.654	.008	14	view →
LUAD	DFS	Median	All	0.849	0.997	.013	9	view →
LSCC	DFS	Tertile	III,IV	1.000	0.717	.040	3	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

LNX1–UCEC (DFS)

Open the UCEC breakdown →