LNX1

Across TCGA cell cohorts, LNX1 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,387 significant associations in total. BONE shows the largest number of these associations.

The most reproducible LNX1-associated GO terms across cancer lineages are Negative regulation of delayed rectifier potassium channel activity, Regulation of blood-brain barrier permeability, and Endosome organization. Each is linked with LNX1 in more than 9 cancer types. Because this analysis shows association rather than direction, both LNX1-to-partner and partner-to-LNX1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of delayed rectifier potassium channel activity grouped by LNX1-low versus LNX1-high in STOMACH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (LNX1→partner) and Y-score (partner→LNX1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	Negative regulation of delayed rectifier potassium channel activity →	+1.338	+1.272	<.001	<.001	3	10
OVARY	Regulation of blood-brain barrier permeability →	+0.212	+1.165	.002	<.001	3	10
OVARY	Endosome organization →	+0.065	+1.144	<.001	<.001	3	10
BREAST	Activation of GTPase activity →	+0.097	+1.061	<.001	<.001	3	9
PANCREAS	Membrane bending →	+0.156	+0.997	.001	<.001	3	9
URINARY_TRACT	Serotonin secretion →	+1.464	+1.222	<.001	.002	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,387 associations by consensus.

Negative regulation of delayed rectifier potassium channel activity by LNX1 expression — STOMACH

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