LNX1-AS2

Across TCGA pan-cancer cohorts, LNX1-AS2 RNA is linked to patient survival in 19 of 34 cancer types, making it the most broadly survival-associated LNX1-AS2 data layer.

The strongest signal is observed in cervical squamous cell carcinoma and endocervical adenocarcinoma (CESC), where higher LNX1-AS2 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated LNX1-AS2 expression acts as an unfavorable survival marker, although some lineages such as ACC and OV show a favorable association.

CESC, ACC, and LGG are the cancer types where LNX1-AS2 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
CESC	DFS	Median	All	0.658	0.825	<.001	50	view →
ACC	DFS	Tertile	IV	0.632	0.127	.001	42	view →
LGG	OS	Tertile	All	0.738	0.907	<.001	36	view →
LUAD	DFS	Tertile	All	0.212	0.523	<.001	35	view →
KIRP	OS	Quartile	III,IV	0.252	0.729	.003	27	view →
OV	OS	Quartile	IV	0.795	0.419	.004	22	view →
UCS	DFS	Quartile	II,III,IV	0.605	0.129	.005	22	view →
DLBC	OS	Tertile	III,IV	0.272	1.000	.017	16	view →
UCEC	DFS	Median	III,IV	0.732	0.850	.022	16	view →
STAD	OS	Tertile	IV	0.179	0.506	.017	15	view →
UVM	OS	Tertile	All	0.387	0.730	.023	12	view →
READ	OS	Quartile	III,IV	1.000	0.701	.009	11	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 19 lineages.

LNX1-AS2–CESC (DFS)

Open the CESC breakdown →