LNX1-AS2

Across TCGA pan-cancer cohorts, LNX1-AS2 RNA differs between tumor and matched normal tissue in 10 of 18 cancer types tested, making tumor–normal expression one of LNX1-AS2’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where LNX1-AS2 RNA is repressed in tumor relative to normal tissue. In most cancer types LNX1-AS2 is over-expressed in tumor, although a few such as KIRC and KIRP show the opposite, repressed pattern.

KIRC, LUAD, and KIRP are the cancer types where LNX1-AS2 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in LNX1-AS2 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRC	Male	II,III,IV	−0.694	<.001	12	view →
LUAD	Male	All	+0.485	<.001	7	view →
KIRP	All	All	−0.408	<.001	6	view →
COAD	Male	All	+0.417	<.001	4	view →
LUSC	All	All	+0.225	<.001	4	view →
PAAD	Male	All	+0.550	.035	2	view →
BRCA	All	IV	+0.549	.014	2	view →
PRAD	All	All	−0.376	<.001	2	view →
CHOL	All	All	+0.392	.021	1	view →
KICH	All	All	−0.390	.033	1	view →
LUSC	Female	III,IV	−0.110	.008	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 11 strongest of 10 lineages.

LNX1-AS2–KIRC

Open the KIRC breakdown →