LNX1-AS1

Across TCGA pan-cancer cohorts, LNX1-AS1 RNA is linked to patient survival in 21 of 34 cancer types, making it the most broadly survival-associated LNX1-AS1 data layer.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher LNX1-AS1 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated LNX1-AS1 expression acts as an unfavorable survival marker, although some lineages such as KIRP and READ show a favorable association.

KIRC, THCA, and UCS are the cancer types where LNX1-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	DFS	Quartile	III,IV	0.511	0.682	.006	59	view →
THCA	DFS	Median	III,IV	0.728	0.949	.001	37	view →
UCS	DFS	Tertile	IV	0.132	0.718	.002	36	view →
THYM	OS	Tertile	All	0.798	0.986	.003	33	view →
SKCM	OS	Tertile	III,IV	0.232	0.721	.010	21	view →
CHOL	OS	Tertile	III,IV	0.275	0.886	.045	18	view →
ESCA	DFS	Median	IV	0.213	0.626	.026	18	view →
TGCT	DFS	Tertile	All	0.703	0.868	.018	18	view →
KIRP	DFS	Tertile	All	0.977	0.896	.031	15	view →
LUSC	DFS	Median	All	0.711	0.801	.002	15	view →
READ	OS	Tertile	III,IV	0.813	0.413	.017	10	view →
MESO	OS	Tertile	IV	0.423	0.622	.048	9	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 21 lineages.

LNX1-AS1–KIRC (DFS)

Open the KIRC breakdown →