LNX1-AS1

Across TCGA pan-cancer cohorts, LNX1-AS1 RNA differs between tumor and matched normal tissue in 6 of 18 cancer types tested, making tumor–normal expression one of LNX1-AS1’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where LNX1-AS1 RNA is repressed in tumor relative to normal tissue. In most cancer types LNX1-AS1 is over-expressed in tumor, although a few such as KIRC and KIRP show the opposite, repressed pattern.

KIRC, KIRP, and LUSC are the cancer types where LNX1-AS1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in LNX1-AS1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRC	Male	All	−0.024	.005	7	view →
KIRP	All	All	−0.045	.003	4	view →
LUSC	Male	All	+0.050	<.001	3	view →
BRCA	Female	All	+0.114	.037	2	view →
BLCA	Female	All	+0.086	.044	2	view →
LIHC	All	II,III,IV	+0.012	.038	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 6 strongest of 6 lineages.

LNX1-AS1–KIRC

Open the KIRC breakdown →