Across TCGA patient cohorts, LNP1 RNA expression is significantly associated with the RNA expression of many other genes, with 19,328 significant associations in total. THYM shows the largest number of these associations.

The most reproducible LNP1-associated genes across cancer lineages are WDR5B, ARL6, and SENP7. Each is linked with LNP1 in more than 31 cancer types. Because this analysis shows association rather than direction, both LNP1-to-partner and partner-to-LNP1 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LNP1→partner) and Y-score (partner→LNP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UVM	WDR5B →	+0.814	+1.941	<.001	<.001	3	32
SCLC	ARL6 →	+0.983	+0.669	<.001	<.001	3	32
THYM	SENP7 →	+0.931	+0.798	<.001	<.001	3	32
THYM	MBTPS1 →	+0.987	+1.027	<.001	<.001	3	32
SCLC	ABHD10 →	+0.869	+0.980	<.001	<.001	3	32
KIRP	TOMM70 →	+0.953	+2.067	<.001	<.001	3	32

Each partner links to its Q-omics profile. Showing the 6 strongest of 19,328 associations by consensus.

Exploration

LNP1 survival (RNA) · tumor vs normal (RNA) · all LNP1 data types