LMOD3

Across TCGA cell cohorts, LMOD3 mutation is significantly associated with the RNA expression of many other genes, with 8 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible LMOD3-associated genes across cancer lineages are OR4A47, C10orf71, and AQP12A. Each is linked with LMOD3 in more than 1 cancer types. Because this analysis shows association rather than direction, both LMOD3-to-partner and partner-to-LMOD3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR4A47 grouped by LMOD3-low versus LMOD3-high in LUNG_NSCLC_LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LMOD3→partner) and Y-score (partner→LMOD3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	OR4A47 →	+0.018	+5.228	<.001	.005	3	2
LUNG_NSCLC_LUAD	C10orf71 →	+0.029	+4.887	<.001	.009	3	1
BLOOD_Leukemia	AQP12A →	+0.093	+3.684	<.001	.004	3	1
BLOOD_Leukemia	LCE2A →	+0.035	+3.969	<.001	.009	3	1
BLOOD_Leukemia	GUCA2A →	+0.026	+3.969	<.001	.009	3	1
BLOOD_Leukemia	CCT8L2 →	+0.009	+3.289	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 8 associations by consensus.

OR4A47 by LMOD3 expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →