LMOD1

Across TCGA cell cohorts, LMOD1 mutation is significantly associated with the RNA expression of many other genes, with 12 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible LMOD1-associated genes across cancer lineages are OR5T2, PRAMEF20, and PRAMEF14. Each is linked with LMOD1 in more than 1 cancer types. Because this analysis shows association rather than direction, both LMOD1-to-partner and partner-to-LMOD1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR5T2 grouped by LMOD1-low versus LMOD1-high in SKIN.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LMOD1→partner) and Y-score (partner→LMOD1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	OR5T2 →	+0.026	+4.273	<.001	.006	3	1
SKIN	PRAMEF20 →	+0.088	+4.273	<.001	.006	3	1
SKIN	PRAMEF14 →	+0.045	+4.273	<.001	.006	3	1
SKIN	PRAMEF33 →	+0.020	+6.000	<.001	<.001	3	1
SKIN	SCYGR10 →	+0.189	+4.684	<.001	.002	3	1
LARGE_INTESTINE	MLNR →	+0.118	+3.807	.002	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 12 associations by consensus.

OR5T2 by LMOD1 expression — SKIN

Explore this box plot interactively →