LMOD1

Across TCGA pan-cancer cohorts, LMOD1 RNA differs between tumor and matched normal tissue in 16 of 18 cancer types tested, making tumor–normal expression one of LMOD1’s most consistent transcriptional readouts.

The strongest signal is observed in bladder urothelial carcinoma (BLCA), where LMOD1 RNA is repressed in tumor relative to normal tissue. In most cancer types LMOD1 is over-expressed in tumor, although a few such as BLCA and THCA show the opposite, repressed pattern.

BLCA, THCA, and KICH are the cancer types where LMOD1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in LMOD1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
BLCA	Male	III,IV	−6.475	<.001	11	view →
THCA	All	IV	−3.817	<.001	11	view →
KICH	Male	II,III,IV	−2.971	<.001	11	view →
COAD	Male	II,III,IV	−3.014	<.001	10	view →
LUAD	Female	III,IV	−2.212	<.001	9	view →
KIRP	Male	All	−2.196	<.001	9	view →
UCEC	All	All	−5.693	<.001	8	view →
LUSC	All	III,IV	−3.028	<.001	8	view →
STAD	Female	All	−3.821	<.001	6	view →
BRCA	All	All	−2.740	<.001	6	view →
HNSC	Male	All	−1.541	<.001	6	view →
LIHC	All	All	+1.150	<.001	6	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 16 lineages.

LMOD1–BLCA

Open the BLCA breakdown →