LMNB2

Across TCGA cell cohorts, LMNB2 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,393 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible LMNB2-associated GO terms across cancer lineages are Positive regulation of mitotic cytokinesis, Chromosome condensation, and Regulation of DNA-templated DNA replication. Each is linked with LMNB2 in more than 19 cancer types. Because this analysis shows association rather than direction, both LMNB2-to-partner and partner-to-LMNB2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of mitotic cytokinesis grouped by LMNB2-low versus LMNB2-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (LMNB2→partner) and Y-score (partner→LMNB2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Positive regulation of mitotic cytokinesis →	+0.176	+1.271	<.001	<.001	3	20
OESOPHAGUS	Chromosome condensation →	+0.227	+1.197	.001	.003	3	19
OESOPHAGUS	Regulation of DNA-templated DNA replication →	+0.124	+1.313	.001	<.001	3	19
CNS	Positive regulation of nuclear cell cycle DNA replication →	+0.143	+0.981	<.001	<.001	3	18
PANCREAS	Negative regulation of cell cycle process →	+0.061	+1.245	<.001	<.001	3	18
OVARY	Cell cycle DNA replication →	+0.133	+1.300	<.001	<.001	3	18

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,393 associations by consensus.

Positive regulation of mitotic cytokinesis by LMNB2 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →