LMNB2

Across TCGA cell cohorts, LMNB2 mutation is significantly associated with the RNA expression of many other genes, with 18 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible LMNB2-associated genes across cancer lineages are LCN1, ANKRD34C, and SPP2. Each is linked with LMNB2 in more than 1 cancer types. Because this analysis shows association rather than direction, both LMNB2-to-partner and partner-to-LMNB2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LCN1 grouped by LMNB2-low versus LMNB2-high in OESOPHAGUS.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LMNB2→partner) and Y-score (partner→LMNB2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	LCN1 →	+0.040	+4.906	<.001	.006	3	1
OESOPHAGUS	ANKRD34C →	+0.016	+4.906	<.001	.006	3	1
OESOPHAGUS	SPP2 →	+0.116	+4.906	<.001	.006	3	1
LARGE_INTESTINE	LCT →	+0.261	+3.464	.009	.004	3	1
LARGE_INTESTINE	TBR1 →	+0.041	+3.555	<.001	.003	3	1
LARGE_INTESTINE	BPIFA1 →	+0.145	+2.688	<.001	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 18 associations by consensus.

LCN1 by LMNB2 expression — OESOPHAGUS

Explore this box plot interactively →