LMNB1

Across TCGA pan-cancer cohorts, LMNB1 mass-spec protein is linked to patient survival in 4 of 34 cancer types, making it a survival-associated LMNB1 data layer compared with 29 for mass-spec protein and 3 for mutation status.

The strongest signal is observed in clear cell renal cell carcinoma (CCRCC), where higher LMNB1 mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated LMNB1 expression acts as an unfavorable survival marker, although some lineages such as CCRCC and COAD show a favorable association.

CCRCC, COAD, and LSCC are the cancer types where LMNB1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
CCRCC	DFS	Tertile	IV	1.000	0.089	.024	17	view →
COAD	DFS	Median	IV	1.000	0.605	.043	12	view →
LSCC	DFS	Quartile	II,III,IV	1.000	0.322	.024	2	view →
LUAD	OS	Tertile	All	0.907	1.000	.029	1	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

LMNB1–CCRCC (DFS)

Open the CCRCC breakdown →