LMF1-AS1

Across TCGA pan-cancer cohorts, LMF1-AS1 RNA is linked to patient survival in 18 of 34 cancer types, making it the most broadly survival-associated LMF1-AS1 data layer.

The strongest signal is observed in pancreatic adenocarcinoma (PAAD), where higher LMF1-AS1 RNA is associated with better disease-free survival. In most high-consensus cancer types, elevated LMF1-AS1 expression acts as an unfavorable survival marker, although some lineages such as PAAD and HNSC show a favorable association.

PAAD, HNSC, and LAML are the cancer types where LMF1-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
PAAD	DFS	Tertile	II,III,IV	0.464	0.270	<.001	85	view →
HNSC	OS	Tertile	All	0.492	0.256	<.001	83	view →
LAML	DFS	Tertile	All	0.499	0.293	.013	22	view →
SKCM	OS	Tertile	IV	0.754	0.142	.006	19	view →
KIRP	DFS	Tertile	IV	0.046	0.762	.026	12	view →
MESO	DFS	Tertile	III,IV	0.124	0.697	.010	12	view →
UCS	OS	Tertile	IV	0.352	1.000	.036	12	view →
UVM	OS	Median	III,IV	0.304	1.000	.008	11	view →
READ	OS	Median	II,III,IV	0.773	0.486	.013	10	view →
OV	OS	Median	II,III,IV	0.282	0.367	.024	8	view →
BRCA	DFS	Tertile	IV	0.426	0.757	.016	8	view →
THCA	DFS	Quartile	III,IV	0.750	0.965	.007	7	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 18 lineages.

LMF1-AS1–PAAD (DFS)

Open the PAAD breakdown →