LMF1-AS1

Across TCGA pan-cancer cohorts, LMF1-AS1 RNA differs between tumor and matched normal tissue in 11 of 18 cancer types tested, making tumor–normal expression one of LMF1-AS1’s most consistent transcriptional readouts.

The strongest signal is observed in lung adenocarcinoma (LUAD), where LMF1-AS1 RNA is repressed in tumor relative to normal tissue. In most cancer types LMF1-AS1 is over-expressed in tumor, although a few such as LUAD and LUSC show the opposite, repressed pattern.

LUAD, LUSC, and BRCA are the cancer types where LMF1-AS1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in LMF1-AS1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
LUAD	Female	III,IV	−0.929	<.001	7	view →
LUSC	Female	All	−0.712	<.001	7	view →
BRCA	Female	II,III,IV	−0.627	<.001	6	view →
BLCA	Male	All	−0.517	.002	6	view →
KICH	All	All	−0.400	<.001	5	view →
KIRP	All	All	−0.180	<.001	5	view →
COAD	Female	All	+0.155	.004	3	view →
STAD	Male	All	+0.123	.014	3	view →
UCEC	All	All	−0.196	.006	2	view →
CHOL	All	All	+0.174	.014	2	view →
KIRC	Male	II,III,IV	−0.112	.017	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 11 strongest of 11 lineages.

LMF1-AS1–LUAD

Open the LUAD breakdown →