LMBR1L

Across TCGA patient cohorts, LMBR1L mutation is significantly associated with the RNA expression of many other genes, with 2,053 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible LMBR1L-associated genes across cancer lineages are LINC01072, RNA5SP355, and VPS37A. Each is linked with LMBR1L in more than 2 cancer types. Because this analysis shows association rather than direction, both LMBR1L-to-partner and partner-to-LMBR1L results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LINC01072 grouped by LMBR1L-low versus LMBR1L-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LMBR1L→partner) and Y-score (partner→LMBR1L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	LINC01072 →	+0.096	+1.903	.003	.009	3	3
BLCA	RNA5SP355 →	+0.203	+4.289	<.001	.007	3	2
UCEC	VPS37A →	+0.574	+2.906	<.001	.001	3	2
UCEC	WHAMM →	+0.675	+2.354	<.001	<.001	3	2
UCEC	SAAL1 →	+0.522	+2.343	<.001	<.001	3	2
UCEC	CLPX →	+0.396	+3.398	.009	.004	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,053 associations by consensus.

LINC01072 by LMBR1L expression — UCEC

Explore this box plot interactively →