LMBR1L

Across TCGA cell cohorts, LMBR1L mutation is significantly associated with the RNA expression of many other genes, with 9 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible LMBR1L-associated genes across cancer lineages are ETDC, ACSM2B, and DIRC1. Each is linked with LMBR1L in more than 1 cancer types. Because this analysis shows association rather than direction, both LMBR1L-to-partner and partner-to-LMBR1L results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ETDC grouped by LMBR1L-low versus LMBR1L-high in LUNG_NSCLC_LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LMBR1L→partner) and Y-score (partner→LMBR1L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	ETDC →	+0.499	+5.228	<.001	.005	3	1
LUNG_NSCLC_LUAD	ACSM2B →	+0.049	+4.887	<.001	.009	3	1
LUNG_SCLC	DIRC1 →	+0.053	+5.643	<.001	.002	3	1
LUNG_SCLC	MUC22 →	+0.016	+5.029	<.001	.006	3	1
LARGE_INTESTINE	MYF6 →	+0.019	+5.415	<.001	.004	3	1
LARGE_INTESTINE	OR1L6 →	+0.036	+6.022	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 9 associations by consensus.

ETDC by LMBR1L expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →