LMBR1

Across TCGA patient cohorts, LMBR1 mutation is significantly associated with the RNA expression of many other genes, with 1,982 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible LMBR1-associated genes across cancer lineages are MIR615, RNA5SP46, and RNU6-842P. Each is linked with LMBR1 in more than 2 cancer types. Because this analysis shows association rather than direction, both LMBR1-to-partner and partner-to-LMBR1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR615 grouped by LMBR1-low versus LMBR1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LMBR1→partner) and Y-score (partner→LMBR1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	MIR615 →	+0.246	+2.428	<.001	<.001	3	3
SKCM	RNA5SP46 →	+0.108	+3.591	<.001	.002	3	2
SKCM	RNU6-842P →	+0.089	+4.769	<.001	.002	3	2
SKCM	LINC02641 →	+0.179	+3.015	.001	.002	3	2
BRCA	MIR3617 →	+0.489	+5.259	<.001	.007	3	2
UCEC	NFATC4 →	-0.451	-2.039	.007	.005	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,982 associations by consensus.

MIR615 by LMBR1 expression — UCEC

Explore this box plot interactively →