LMBR1

Across TCGA cell cohorts, LMBR1 mutation is significantly associated with the RNA expression of many other genes, with 3 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible LMBR1-associated genes across cancer lineages are CLEC4D, TSBP1, and GYPB. Each is linked with LMBR1 in more than 1 cancer types. Because this analysis shows association rather than direction, both LMBR1-to-partner and partner-to-LMBR1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CLEC4D grouped by LMBR1-low versus LMBR1-high in LUNG_NSCLC_LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LMBR1→partner) and Y-score (partner→LMBR1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	CLEC4D →	+0.052	+4.093	<.001	.004	3	1
LUNG_NSCLC_LUAD	TSBP1 →	+0.109	+3.544	<.001	.009	3	1
LUNG_NSCLC_LUAD	GYPB →	+0.080	+3.544	.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

CLEC4D by LMBR1 expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →