LMAN1L

mass-spec protein — tumor vs normal
Tumor vs Normalmass-specBox plot · TCGA cohorts

Across TCGA pan-cancer cohorts, LMAN1L mass-spec protein differs between tumor and matched normal tissue in 2 of 18 cancer types tested, making tumor–normal expression one of LMAN1L’s most consistent transcriptional readouts.

The strongest signal is observed in colon adenocarcinoma (COAD), where LMAN1L mass-spec protein is more highly expressed in tumor relative to normal tissue. In most cancer types LMAN1L is over-expressed in tumor.

COAD and LSCC are the cancer types where LMAN1L tumor–normal differential expression is most reproducible.

mass-spec protein tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in LMAN1L mass-spec protein (log2); positive values indicate higher expression in tumor. p-values are from the differential-expression test.
LineageGenderStageFold-changepSampling consensus
COADFemaleAll+0.729<.00110view →
LSCCAllAll+0.649<.0015view →
Pink = over-expressed in tumor, green = repressed in tumor. Showing the 2 strongest of 2 lineages.

LMAN1L–COAD

Tumor-vs-normal mass-spec protein box plot for LMAN1L in COAD.

Open the COAD breakdown →

Exploration