LLCFC1

Across TCGA cell cohorts, LLCFC1 mutation is significantly associated with the RNA expression of many other genes, with 3 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible LLCFC1-associated genes across cancer lineages are C1QC, GYPB, and OR2M5. Each is linked with LLCFC1 in more than 1 cancer types. Because this analysis shows association rather than direction, both LLCFC1-to-partner and partner-to-LLCFC1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, C1QC grouped by LLCFC1-low versus LLCFC1-high in LUNG_NSCLC_LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LLCFC1→partner) and Y-score (partner→LLCFC1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	C1QC →	+0.024	+5.813	<.001	<.001	3	1
LUNG_NSCLC_LUAD	GYPB →	+0.124	+4.544	<.001	.003	3	1
LARGE_INTESTINE	OR2M5 →	+0.022	+5.415	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

C1QC by LLCFC1 expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →