LLCFC1

Across TCGA pan-cancer cohorts, LLCFC1 RNA differs between tumor and matched normal tissue in 6 of 18 cancer types tested, making tumor–normal expression one of LLCFC1’s most consistent transcriptional readouts.

The strongest signal is observed in kidney chromophobe (KICH), where LLCFC1 RNA is repressed in tumor relative to normal tissue. In most cancer types LLCFC1 is over-expressed in tumor, although a few such as KICH and KIRC show the opposite, repressed pattern.

KICH, KIRC, and THCA are the cancer types where LLCFC1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in LLCFC1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KICH	Male	II,III,IV	−0.323	<.001	9	view →
KIRC	Male	III,IV	−0.198	<.001	7	view →
THCA	All	All	−0.121	<.001	4	view →
CHOL	All	All	+0.150	.021	1	view →
HNSC	Female	IV	−0.088	.034	1	view →
COAD	Female	II,III,IV	+0.040	.040	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 6 strongest of 6 lineages.

LLCFC1–KICH

Open the KICH breakdown →