LIX1L-AS1

Across TCGA pan-cancer cohorts, LIX1L-AS1 RNA is linked to patient survival in 19 of 34 cancer types, making it the most broadly survival-associated LIX1L-AS1 data layer.

The strongest signal is observed in adrenocortical carcinoma (ACC), where higher LIX1L-AS1 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated LIX1L-AS1 expression acts as an unfavorable survival marker, although some lineages such as CHOL and ESCA show a favorable association.

ACC, KIRC, and LUAD are the cancer types where LIX1L-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
ACC	DFS	Median	All	0.203	0.685	<.001	118	view →
KIRC	DFS	Median	II,III,IV	0.424	0.610	.001	57	view →
LUAD	OS	Quartile	II,III,IV	0.574	0.840	.002	56	view →
UVM	DFS	Tertile	III,IV	0.363	0.857	.005	44	view →
CHOL	DFS	Tertile	All	0.580	0.230	.004	21	view →
ESCA	DFS	Tertile	All	1.000	0.437	.008	12	view →
LGG	DFS	Quartile	All	0.638	0.814	<.001	10	view →
THCA	DFS	Tertile	IV	0.949	0.540	.008	9	view →
READ	OS	Median	III,IV	0.467	0.854	.007	9	view →
GBM	DFS	Tertile	All	0.402	0.179	.011	6	view →
MESO	DFS	Quartile	IV	0.086	0.508	.006	6	view →
LAML	DFS	Median	All	0.674	0.457	.041	6	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 19 lineages.

LIX1L-AS1–ACC (DFS)

Open the ACC breakdown →