LIX1L-AS1

Across TCGA pan-cancer cohorts, LIX1L-AS1 RNA differs between tumor and matched normal tissue in 6 of 18 cancer types tested, making tumor–normal expression one of LIX1L-AS1’s most consistent transcriptional readouts.

The strongest signal is observed in kidney chromophobe (KICH), where LIX1L-AS1 RNA is repressed in tumor relative to normal tissue. In most cancer types LIX1L-AS1 is over-expressed in tumor, although a few such as KICH and THCA show the opposite, repressed pattern.

KICH, THCA, and LIHC are the cancer types where LIX1L-AS1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in LIX1L-AS1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KICH	Female	All	−0.578	<.001	10	view →
THCA	Male	All	−0.302	<.001	9	view →
LIHC	Male	II,III,IV	+0.365	<.001	8	view →
HNSC	All	All	+0.109	.002	6	view →
UCEC	All	All	−0.221	.005	4	view →
CHOL	All	All	+0.325	.014	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 6 strongest of 6 lineages.

LIX1L-AS1–KICH

Open the KICH breakdown →