LIX1-AS1

Across TCGA pan-cancer cohorts, LIX1-AS1 RNA differs between tumor and matched normal tissue in 8 of 18 cancer types tested, making tumor–normal expression one of LIX1-AS1’s most consistent transcriptional readouts.

The strongest signal is observed in stomach adenocarcinoma (STAD), where LIX1-AS1 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types LIX1-AS1 is over-expressed in tumor, although a few such as THCA and LUSC show the opposite, repressed pattern.

STAD, HNSC, and LIHC are the cancer types where LIX1-AS1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in LIX1-AS1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
STAD	Female	All	+0.305	.017	5	view →
HNSC	All	All	+0.043	.009	5	view →
LIHC	All	All	+0.031	<.001	5	view →
BRCA	Female	All	+0.089	.015	4	view →
THCA	All	All	−0.096	.011	3	view →
CHOL	All	All	+0.165	<.001	2	view →
LUSC	Male	III,IV	−0.169	.039	1	view →
KIRP	All	All	−0.059	.031	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 8 strongest of 8 lineages.

LIX1-AS1–STAD

Open the STAD breakdown →