LIPT2

Across TCGA patient cohorts, LIPT2 RNA expression is significantly associated with the protein abundance of many other proteins, with 13,463 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible LIPT2-associated proteins across cancer lineages are POLD3, SFXN3, and POLD1. Each is linked with LIPT2 in more than 5 cancer types. Because this analysis shows association rather than direction, both LIPT2-to-partner and partner-to-LIPT2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, LIPT2 versus POLD3 in BRCA, with a Pearson correlation of 0.43.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (LIPT2→partner) and Y-score (partner→LIPT2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	POLD3 →	+0.590	+0.550	<.001	<.001	3	6
UCEC	SFXN3 →	-0.424	-0.484	<.001	.001	3	5
LSCC	POLD1 →	+0.356	+0.598	<.001	<.001	3	5
GBM	PPP1R18_S368 →	-0.562	-0.319	.001	.001	3	5
LSCC	PYGL →	-0.414	-0.638	.001	<.001	3	5
OV	RFC4 →	+0.449	+0.620	<.001	.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,463 associations by consensus.

LIPT2 vs POLD3 — BRCA

Explore this scatter interactively →