LIPM

Across TCGA cell cohorts, LIPM RNA expression is significantly associated with the go_rna of many other GO terms, with 2,713 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible LIPM-associated GO terms across cancer lineages are Response to indole-3-methanol, Serotonin secretion, and Serotonin production involved in inflammatory response. Each is linked with LIPM in more than 8 cancer types. Because this analysis shows association rather than direction, both LIPM-to-partner and partner-to-LIPM results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Response to indole-3-methanol grouped by LIPM-low versus LIPM-high in STOMACH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (LIPM→partner) and Y-score (partner→LIPM) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	Response to indole-3-methanol →	+0.197	+0.423	<.001	<.001	3	9
PANCREAS	Serotonin secretion →	+1.172	+0.550	.002	<.001	3	9
PANCREAS	Serotonin production involved in inflammatory response →	+1.172	+0.550	.002	<.001	3	9
PANCREAS	Serotonin secretion involved in inflammatory response →	+1.172	+0.550	.002	<.001	3	9
STOMACH	Bundle of His cell to Purkinje myocyte communication →	+0.325	+0.486	<.001	<.001	3	8
OESOPHAGUS	Regulation of heart rate by cardiac conduction →	+0.266	+0.380	.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,713 associations by consensus.

Response to indole-3-methanol by LIPM expression — STOMACH

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