Across TCGA patient cohorts, LIPJ mutation is significantly associated with the RNA expression of many other genes, with 3,913 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible LIPJ-associated genes across cancer lineages are MIR629, ARL6IP1P3, and PSMC3IP. Each is linked with LIPJ in more than 1 cancer types. Because this analysis shows association rather than direction, both LIPJ-to-partner and partner-to-LIPJ results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LIPJ→partner) and Y-score (partner→LIPJ) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CESC	MIR629 →	+0.502	+5.418	<.001	.005	3	2
SKCM	ARL6IP1P3 →	+0.107	+2.763	<.001	.003	3	2
UCEC	PSMC3IP →	+0.958	+3.010	<.001	<.001	3	2
UCEC	COX11 →	+0.641	+3.021	<.001	<.001	3	2
UCEC	TUBA1C →	+0.783	+3.467	.001	.002	3	2
UCEC	NDUFAB1 →	+0.465	+3.053	.005	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,913 associations by consensus.

Exploration

LIPJ survival (RNA) · tumor vs normal (RNA) · all LIPJ data types