LIPE

Across TCGA cell cohorts, LIPE RNA expression is significantly associated with the go_rna of many other GO terms, with 4,128 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible LIPE-associated GO terms across cancer lineages are Negative regulation of calcium ion export across plasma membrane, Nucleosome organization, and Nucleosome disassembly. Each is linked with LIPE in more than 8 cancer types. Because this analysis shows association rather than direction, both LIPE-to-partner and partner-to-LIPE results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of calcium ion export across plasma membrane grouped by LIPE-low versus LIPE-high in KIDNEY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (LIPE→partner) and Y-score (partner→LIPE) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
KIDNEY	Negative regulation of calcium ion export across plasma membrane →	+0.073	+1.008	.001	<.001	3	8
LUNG_SCLC	Nucleosome organization →	+0.081	+1.448	.002	.001	3	8
BLOOD_Lymphoma	Nucleosome disassembly →	+0.101	+1.491	.004	.001	2	9
LUNG_NSCLC_LUAD	Negative regulation of mRNA splicing, via spliceosome →	+0.071	+1.190	<.001	<.001	3	8
CNS	Cellular response to forskolin →	+0.160	+0.822	<.001	.005	3	7
LUNG_SCLC	Regulation of double-strand break repair →	+0.071	+1.763	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,128 associations by consensus.

Negative regulation of calcium ion export across plasma membrane by LIPE expression — KIDNEY

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