LIPC-AS1

RNA & survival
SurvivalRNAKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, LIPC-AS1 RNA is linked to patient survival in 20 of 34 cancer types, making it the most broadly survival-associated LIPC-AS1 data layer.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher LIPC-AS1 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated LIPC-AS1 expression acts as an unfavorable survival marker, although some lineages such as BLCA and THYM show a favorable association.

UCEC, BLCA, and LGG are the cancer types where LIPC-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
UCECOSTertileAll0.5330.732.00194view →
BLCAOSMedianAll0.5400.349.00471view →
LGGDFSMedianAll0.6480.791<.00147view →
THCAOSQuartileAll0.9471.000.00531view →
ACCOSTertileAll0.2050.728.00430view →
THYMOSTertileAll1.0000.747.00722view →
GBMOSQuartileAll0.2690.458.00321view →
KICHOSMedianIII,IV1.0000.781.01119view →
SKCMOSTertileIV0.4500.806.04018view →
LIHCDFSQuartileAll0.2050.358.02412view →
READDFSTertileIV0.2950.657.0359view →
SARCOSQuartileAll0.8120.529.0255view →
Pink = unfavorable, green = favorable. Showing the 12 strongest of 20 lineages.

LIPC-AS1–UCEC (OS)

Kaplan–Meier survival curve for LIPC-AS1 RNA-high vs -low samples in UCEC.

Open the UCEC breakdown →

Exploration