LIPC-AS1

Across TCGA pan-cancer cohorts, LIPC-AS1 RNA differs between tumor and matched normal tissue in 7 of 18 cancer types tested, making tumor–normal expression one of LIPC-AS1’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where LIPC-AS1 RNA is repressed in tumor relative to normal tissue. In most cancer types LIPC-AS1 is over-expressed in tumor, although a few such as KIRC and KICH show the opposite, repressed pattern.

KIRC, BLCA, and KICH are the cancer types where LIPC-AS1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in LIPC-AS1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRC	Male	All	−0.225	<.001	11	view →
BLCA	Male	IV	+0.520	.001	8	view →
KICH	Male	All	−0.620	<.001	7	view →
THCA	Male	All	−0.118	<.001	7	view →
STAD	Male	All	+0.055	<.001	4	view →
KIRP	All	IV	+0.170	.029	2	view →
LIHC	All	II,III,IV	+0.046	.038	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 7 strongest of 7 lineages.

LIPC-AS1–KIRC

Open the KIRC breakdown →