LIPA

Across TCGA patient cohorts, LIPA RNA expression is significantly associated with the protein abundance of many other proteins, with 12,964 significant associations in total. GBM shows the largest number of these associations.

The most reproducible LIPA-associated proteins across cancer lineages are RENBP, ITGAL, and LSP1. Each is linked with LIPA in more than 7 cancer types. Because this analysis shows association rather than direction, both LIPA-to-partner and partner-to-LIPA results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, LIPA versus RENBP in HNSC, with a Pearson correlation of 0.25.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (LIPA→partner) and Y-score (partner→LIPA) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	RENBP →	+0.488	+0.694	<.001	<.001	2	8
PDAC	ITGAL →	+0.441	+0.498	<.001	<.001	3	7
GBM	LSP1 →	+0.770	+0.896	<.001	<.001	3	7
GBM	NCKAP1L →	+0.573	+0.701	<.001	<.001	3	7
PDAC	PIK3CG_S974 →	+0.734	+0.478	<.001	<.001	3	6
GBM	PIP4K2A →	+0.431	+0.809	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,964 associations by consensus.

LIPA vs RENBP — HNSC

Explore this scatter interactively →