Across TCGA pan-cancer cohorts, LINC02655 RNA differs between tumor and matched normal tissue in 3 of 18 cancer types tested, making tumor–normal expression one of LINC02655’s most consistent transcriptional readouts.
The strongest signal is observed in lung squamous cell carcinoma (LUSC), where LINC02655 RNA is repressed in tumor relative to normal tissue. In most cancer types LINC02655 is over-expressed in tumor, although a few such as LUSC and LUAD show the opposite, repressed pattern.
LUSC, LUAD, and THCA are the cancer types where LINC02655 tumor–normal differential expression is most reproducible.