Across TCGA pan-cancer cohorts, LINC02653 RNA differs between tumor and matched normal tissue in 3 of 18 cancer types tested, making tumor–normal expression one of LINC02653’s most consistent transcriptional readouts.
The strongest signal is observed in breast invasive carcinoma (BRCA), where LINC02653 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types LINC02653 is over-expressed in tumor.
BRCA, LUSC, and LUAD are the cancer types where LINC02653 tumor–normal differential expression is most reproducible.