Across TCGA pan-cancer cohorts, LINC02648 RNA differs between tumor and matched normal tissue in 8 of 18 cancer types tested, making tumor–normal expression one of LINC02648’s most consistent transcriptional readouts.
The strongest signal is observed in kidney chromophobe (KICH), where LINC02648 RNA is repressed in tumor relative to normal tissue. In most cancer types LINC02648 is over-expressed in tumor, although a few such as KICH and THCA show the opposite, repressed pattern.
KICH, THCA, and LUSC are the cancer types where LINC02648 tumor–normal differential expression is most reproducible.
RNA tumor vs normal associations by lineage
Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in LINC02648 RNA (log2); positive values indicate higher expression in tumor. p-values are from the differential-expression test.