LINC02643

Across TCGA pan-cancer cohorts, LINC02643 RNA differs between tumor and matched normal tissue in 5 of 18 cancer types tested, making tumor–normal expression one of LINC02643’s most consistent transcriptional readouts.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where LINC02643 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types LINC02643 is over-expressed in tumor, although a few such as BRCA show the opposite, repressed pattern.

HNSC, KIRC, and BLCA are the cancer types where LINC02643 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in LINC02643 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
HNSC	All	III,IV	+0.230	<.001	11	view →
KIRC	Male	All	+0.058	.001	4	view →
BLCA	All	All	+0.148	.017	3	view →
LUAD	All	All	+0.075	.017	3	view →
BRCA	All	III,IV	−0.058	.032	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 5 strongest of 5 lineages.

LINC02643–HNSC

Open the HNSC breakdown →