Across TCGA pan-cancer cohorts, LINC02549 RNA differs between tumor and matched normal tissue in 4 of 18 cancer types tested, making tumor–normal expression one of LINC02549’s most consistent transcriptional readouts.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where LINC02549 RNA is repressed in tumor relative to normal tissue. In most cancer types LINC02549 is over-expressed in tumor, although a few such as HNSC show the opposite, repressed pattern.

HNSC, THCA, and LUAD are the cancer types where LINC02549 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in LINC02549 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
HNSC	All	All	−0.113	.005	6	view →
THCA	All	All	+0.151	<.001	5	view →
LUAD	All	All	+0.048	.009	2	view →
KIRP	All	All	+0.176	.027	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 4 strongest of 4 lineages.

Exploration

Same gene, other analysis: LINC02549 RNA expression & survival · all LINC02549 data types