LINC02481

Across TCGA pan-cancer cohorts, LINC02481 RNA is linked to patient survival in 22 of 34 cancer types, making it the most broadly survival-associated LINC02481 data layer.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher LINC02481 RNA is associated with better disease-free survival. In most high-consensus cancer types, elevated LINC02481 expression acts as an unfavorable survival marker, although some lineages such as HNSC and SKCM show a favorable association.

HNSC, SKCM, and CESC are the cancer types where LINC02481 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
HNSC	DFS	Median	All	0.757	0.634	<.001	165	view →
SKCM	OS	Median	All	0.445	0.260	<.001	133	view →
CESC	OS	Median	All	0.699	0.486	.001	74	view →
BLCA	OS	Quartile	All	0.703	0.488	<.001	64	view →
READ	OS	Quartile	II,III,IV	0.823	0.284	.002	29	view →
UVM	DFS	Quartile	All	0.486	0.818	.007	25	view →
KICH	OS	Median	All	0.859	0.982	.011	24	view →
THYM	OS	Median	All	0.733	1.000	.001	21	view →
THCA	OS	Median	All	1.000	0.822	.006	19	view →
LIHC	DFS	Quartile	All	0.501	0.291	<.001	19	view →
KIRP	DFS	Median	III,IV	0.448	0.724	.010	16	view →
LAML	DFS	Quartile	All	0.673	0.251	.002	16	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 22 lineages.

LINC02481–HNSC (DFS)

Open the HNSC breakdown →