LINC02481

Across TCGA pan-cancer cohorts, LINC02481 RNA differs between tumor and matched normal tissue in 12 of 18 cancer types tested, making tumor–normal expression one of LINC02481’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where LINC02481 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types LINC02481 is over-expressed in tumor, although a few such as LUSC and LUAD show the opposite, repressed pattern.

KIRC, LUSC, and COAD are the cancer types where LINC02481 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in LINC02481 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRC	Male	All	+0.385	<.001	9	view →
LUSC	Male	II,III,IV	−0.875	<.001	8	view →
COAD	Male	All	+0.492	<.001	7	view →
BRCA	All	All	+0.322	<.001	6	view →
STAD	All	All	+0.534	<.001	5	view →
THCA	All	All	+0.450	<.001	4	view →
LUAD	All	III,IV	−0.386	.008	3	view →
CHOL	All	All	+0.540	.013	2	view →
PRAD	All	All	+0.385	<.001	2	view →
KICH	All	All	−0.228	.003	2	view →
READ	Female	All	+0.787	.039	1	view →
LIHC	Female	All	+0.187	.018	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 12 lineages.

LINC02481–KIRC

Open the KIRC breakdown →